NEUTRALIZATION OF INFLUENZA A VIRUS BY HUMAN SERUM
نویسندگان
چکیده
منابع مشابه
Neutralization of Influenza a Virus by Human Serum
A linear relationship exists between the quantity of human serum used and the quantity of influenza A virus neutralized. By means of this relationship it is possible to determine the maximum quantity of virus which a given human serum can neutralize. This quantity, the neutralizing capacity, is a fixed value and, unlike the serum dilution end point, is independent of the amount of virus used in...
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A linear relationship exists between the logarithm of the quantity of epidemic influenza virus neutralized and the logarithm of the quantity of antiserum which is capable of achieving this result. This relationship is the same for the serum of a ferret convalescent from experimental influenza as for the serum of a rabbit immunized with the virus. By means of the linear relationship between viru...
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Human monoclonal antibodies have been identified which neutralize broad spectra of influenza A or B viruses. Here, we dissect the mechanisms by which such antibodies interfere with infectivity. We distinguish four mechanisms that link the conserved hemagglutinin (HA) epitopes of broadly neutralizing antibodies to critical processes in the viral life cycle. HA-stem binding antibodies can act int...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1941
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.73.3.327